V73G (p.Val73Gly) variant of TNNI1 (Troponin I, slow skeletal muscle)
V73G (p.Val73Gly) in TNNI1 (Troponin I, slow skeletal muscle) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
V73G (p.Val73Gly) variant details
- p.Val73Gly
- gnomAD 1-201413093-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.787
- REVEL 0.93
- CADD 33.00
- PolyPhen-2 0.81
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available