L59P (p.Leu59Pro) variant of TNNI1 (Troponin I, slow skeletal muscle)
L59P (p.Leu59Pro) in TNNI1 (Troponin I, slow skeletal muscle) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
L59P (p.Leu59Pro) variant details
- p.Leu59Pro
- gnomAD 1-201414531-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.736
- REVEL 0.82
- CADD 25.20
- PolyPhen-2 0.66
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available