L59I (p.Leu59Ile) variant of TNNI1 (Troponin I, slow skeletal muscle)
L59I (p.Leu59Ile) in TNNI1 (Troponin I, slow skeletal muscle) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
L59I (p.Leu59Ile) variant details
- p.Leu59Ile
- gnomAD 1-201414532-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.25
- CADD 21.70
- PolyPhen-2 0.17
- SIFT 0.28
- Population evidence available
- Structural context available
- Literature evidence available