I10M (p.Ile10Met) variant of TNNI1 (Troponin I, slow skeletal muscle)
I10M (p.Ile10Met) in TNNI1 (Troponin I, slow skeletal muscle) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
I10M (p.Ile10Met) variant details
- p.Ile10Met
- gnomAD rs1162259668
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.54
- CADD 22.10
- PolyPhen-2 0.97
- SIFT 0.69
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available