C66W (p.Cys66Trp) variant of TNNI1 (Troponin I, slow skeletal muscle)
C66W (p.Cys66Trp) in TNNI1 (Troponin I, slow skeletal muscle) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
C66W (p.Cys66Trp) variant details
- p.Cys66Trp
- gnomAD 1-201413113-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.89
- CADD 29.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available