C35* (p.Cys35Ter) variant of TNNC1 (P63316)
C35* (p.Cys35Ter) in TNNC1 (P63316) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
C35* (p.Cys35Ter) variant details
- p.Cys35Ter
- gnomAD 19-55156320-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.47
- CADD 23.70
- PolyPhen-2 0.55
- SIFT 0.33
- Population evidence available
- Structural context available
- Literature evidence available