R60K (p.Arg60Lys) variant of TNFRSF9 (Q07011)
R60K (p.Arg60Lys) in TNFRSF9 (Q07011) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
R60K (p.Arg60Lys) variant details
- p.Arg60Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0489
- REVEL 0.03
- CADD 0.04
- PolyPhen-2 0.01
- SIFT 0.95
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available