L12R (p.Leu12Arg) variant of TNFRSF9 (Q07011)
L12R (p.Leu12Arg) in TNFRSF9 (Q07011) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L12R (p.Leu12Arg) variant details
- p.Leu12Arg
- TOPMed rs1639877281
- gnomAD rs1639877281
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.14
- CADD 20.10
- PolyPhen-2 0.15
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available