L112Q (p.Leu112Gln) variant of TNFRSF9 (Q07011)
L112Q (p.Leu112Gln) in TNFRSF9 (Q07011) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L112Q (p.Leu112Gln) variant details
- p.Leu112Gln
- gnomAD rs1489523268
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.43
- CADD 17.60
- PolyPhen-2 0.49
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 5.4e-05)
- Structural context available