L112M (p.Leu112Met) variant of TNFRSF9 (Q07011)
L112M (p.Leu112Met) in TNFRSF9 (Q07011) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L112M (p.Leu112Met) variant details
- p.Leu112Met
- gnomAD rs1194429681
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.33
- CADD 3.71
- PolyPhen-2 0.64
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 9.8e-05)
- Structural context available