K76R (p.Lys76Arg) variant of TNFRSF9 (Q07011)
K76R (p.Lys76Arg) in TNFRSF9 (Q07011) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
K76R (p.Lys76Arg) variant details
- p.Lys76Arg
- gnomAD rs1475856415
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.14
- CADD 15.50
- PolyPhen-2 0.02
- SIFT 0.34
- ClinVar: Uncertain significance (not provided)
- UniProt: Uncertain significance
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available