E85D (p.Glu85Asp) variant of TNFRSF9 (Q07011)
E85D (p.Glu85Asp) in TNFRSF9 (Q07011) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
E85D (p.Glu85Asp) variant details
- p.Glu85Asp
- TOPMed rs1214393986
- gnomAD rs1214393986
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.60
- CADD 22.60
- PolyPhen-2 0.92
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available