C117G (p.Cys117Gly) variant of TNFRSF9 (Q07011)
C117G (p.Cys117Gly) in TNFRSF9 (Q07011) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
C117G (p.Cys117Gly) variant details
- p.Cys117Gly
- ESP rs371033313
- ExAC rs371033313
- TOPMed rs371033313
- gnomAD rs371033313
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- REVEL 0.86
- CADD 26.80
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available