A84T (p.Ala84Thr) variant of TNFRSF9 (Q07011)
A84T (p.Ala84Thr) in TNFRSF9 (Q07011) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A84T (p.Ala84Thr) variant details
- p.Ala84Thr
- rs372213895
- ESP rs372213895
- ExAC rs372213895
- TOPMed rs372213895
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.26
- CADD 4.58
- PolyPhen-2 0.15
- SIFT 0.17
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available