S59Y (p.Ser59Tyr) variant of TNFRSF4 (P43489)
S59Y (p.Ser59Tyr) in TNFRSF4 (P43489) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
S59Y (p.Ser59Tyr) variant details
- p.Ser59Tyr
- ExAC rs746967425
- TOPMed rs746967425
- gnomAD rs746967425
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.35
- CADD 4.72
- PolyPhen-2 0.69
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available