N73K (p.Asn73Lys) variant of TNFRSF4 (P43489)
N73K (p.Asn73Lys) in TNFRSF4 (P43489) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
N73K (p.Asn73Lys) variant details
- p.Asn73Lys
- ExAC rs746769533
- TOPMed rs746769533
- gnomAD rs746769533
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.36
- CADD 9.81
- PolyPhen-2 0.99
- SIFT 0.00
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the South Asian population (allele frequency 1.2e-05)