L8M (p.Leu8Met) variant of TNFRSF4 (P43489)
L8M (p.Leu8Met) in TNFRSF4 (P43489) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L8M (p.Leu8Met) variant details
- p.Leu8Met
- Ensembl rs2100956977
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.10
- CADD 10.40
- PolyPhen-2 0.23
- SIFT 0.15
- EBI: Likely benign
- UniProt: Likely benign
- Population evidence available
- Structural context available