E45Q (p.Glu45Gln) variant of TNFRSF4 (P43489)
E45Q (p.Glu45Gln) in TNFRSF4 (P43489) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data.
E45Q (p.Glu45Gln) variant details
- p.Glu45Gln
- gnomAD rs1365748174
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.24
- CADD 23.70
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)