C125R (p.Cys125Arg) variant of TNFRSF4 (P43489)
C125R (p.Cys125Arg) in TNFRSF4 (P43489) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data.
C125R (p.Cys125Arg) variant details
- p.Cys125Arg
- gnomAD rs1397660394
- Missense
- Variant Prioritization Score for Impact Estimate 0.717
- REVEL 0.79
- CADD 24.90
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.3e-05)