W7L (p.Trp7Leu) variant of TNFRSF1B (P20333)
W7L (p.Trp7Leu) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data, published literature, and structural context.
W7L (p.Trp7Leu) variant details
- p.Trp7Leu
- gnomAD 1-12167111-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.542
- REVEL 0.51
- MetaLR 0.85
- MetaSVM 0.26
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available