W17S (p.Trp17Ser) variant of TNFRSF1B (P20333)
W17S (p.Trp17Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
W17S (p.Trp17Ser) variant details
- p.Trp17Ser
- gnomAD 1-12167141-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.55
- MetaLR 0.76
- MetaSVM 0.17
- CADD 25.90
- PolyPhen-2 0.63
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available