W17L (p.Trp17Leu) variant of TNFRSF1B (P20333)
W17L (p.Trp17Leu) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
W17L (p.Trp17Leu) variant details
- p.Trp17Leu
- gnomAD 1-12167141-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.30
- MetaLR 0.63
- MetaSVM -0.43
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.37
- Population evidence available
- Structural context available
- Literature evidence available