V6I (p.Val6Ile) variant of TNFRSF1B (P20333)
V6I (p.Val6Ile) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V6I (p.Val6Ile) variant details
- p.Val6Ile
- 1000Genomes rs543515279
- ExAC rs543515279
- TOPMed rs543515279
- gnomAD rs543515279
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.12
- MetaLR 0.57
- MetaSVM -0.47
- CADD 7.50
- PolyPhen-2 0.01
- SIFT 0.46
- Most common in the HGDP:MAYA population (allele frequency 0.026)
- Structural context available