V6A (p.Val6Ala) variant of TNFRSF1B (P20333)
V6A (p.Val6Ala) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V6A (p.Val6Ala) variant details
- p.Val6Ala
- gnomAD rs1333138678
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.18
- MetaLR 0.58
- MetaSVM -0.41
- CADD 20.10
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available