P34R (p.Pro34Arg) variant of TNFRSF1B (P20333)
P34R (p.Pro34Arg) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P34R (p.Pro34Arg) variant details
- p.Pro34Arg
- ExAC rs760020939
- TOPMed rs760020939
- gnomAD rs760020939
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.27
- MetaLR 0.77
- MetaSVM -0.05
- CADD 14.20
- PolyPhen-2 0.82
- SIFT 0.14
- Most common in the HGDP:SINDHI population (allele frequency 0.023)
- Structural context available