L23V (p.Leu23Val) variant of TNFRSF1B (P20333)
L23V (p.Leu23Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L23V (p.Leu23Val) variant details
- p.Leu23Val
- gnomAD 1-12167158-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.20
- MetaLR 0.46
- MetaSVM -0.37
- CADD 6.31
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available