L23S (p.Leu23Ser) variant of TNFRSF1B (P20333)
L23S (p.Leu23Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L23S (p.Leu23Ser) variant details
- p.Leu23Ser
- gnomAD 1-12167159-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.28
- MetaLR 0.60
- MetaSVM -0.38
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available