L23M (p.Leu23Met) variant of TNFRSF1B (P20333)
L23M (p.Leu23Met) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
L23M (p.Leu23Met) variant details
- p.Leu23Met
- gnomAD 1-12167158-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.27
- MetaLR 0.54
- MetaSVM -0.23
- CADD 17.10
- PolyPhen-2 0.11
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available