L16V (p.Leu16Val) variant of TNFRSF1B (P20333)
L16V (p.Leu16Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L16V (p.Leu16Val) variant details
- p.Leu16Val
- gnomAD 1-12167137-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.30
- MetaLR 0.59
- MetaSVM -0.22
- CADD 22.60
- PolyPhen-2 0.07
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available