L16I (p.Leu16Ile) variant of TNFRSF1B (P20333)
L16I (p.Leu16Ile) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L16I (p.Leu16Ile) variant details
- p.Leu16Ile
- gnomAD 1-12167137-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.31
- MetaLR 0.60
- MetaSVM -0.22
- CADD 22.50
- PolyPhen-2 0.10
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available