L16F (p.Leu16Phe) variant of TNFRSF1B (P20333)
L16F (p.Leu16Phe) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- gnomAD 1-12167137-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.24
- MetaLR 0.61
- MetaSVM -0.36
- CADD 22.70
- PolyPhen-2 0.01
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available