L14Q (p.Leu14Gln) variant of TNFRSF1B (P20333)
L14Q (p.Leu14Gln) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L14Q (p.Leu14Gln) variant details
- p.Leu14Gln
- gnomAD 1-12167132-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- REVEL 0.53
- MetaLR 0.79
- MetaSVM 0.03
- CADD 24.70
- PolyPhen-2 0.68
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available