L14M (p.Leu14Met) variant of TNFRSF1B (P20333)
L14M (p.Leu14Met) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
L14M (p.Leu14Met) variant details
- p.Leu14Met
- gnomAD 1-12167131-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.37
- MetaLR 0.76
- MetaSVM 0.03
- CADD 24.00
- PolyPhen-2 0.58
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available