L10V (p.Leu10Val) variant of TNFRSF1B (P20333)
L10V (p.Leu10Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- gnomAD 1-12167119-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.44
- MetaLR 0.86
- MetaSVM 0.21
- CADD 24.50
- PolyPhen-2 0.98
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available