L10Q (p.Leu10Gln) variant of TNFRSF1B (P20333)
L10Q (p.Leu10Gln) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
L10Q (p.Leu10Gln) variant details
- p.Leu10Gln
- gnomAD 1-12167120-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.62
- MetaLR 0.88
- MetaSVM 0.28
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available