H21R (p.His21Arg) variant of TNFRSF1B (P20333)
H21R (p.His21Arg) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
H21R (p.His21Arg) variant details
- p.His21Arg
- TOPMed rs1016755763
- gnomAD rs1016755763
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.24
- MetaLR 0.50
- MetaSVM -0.45
- CADD 8.71
- PolyPhen-2 0.00
- SIFT 0.86
- Most common in the REMAINING population (allele frequency 8.7e-05)
- Structural context available