H21Q (p.His21Gln) variant of TNFRSF1B (P20333)
H21Q (p.His21Gln) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
H21Q (p.His21Gln) variant details
- p.His21Gln
- gnomAD 1-12167154-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.22
- MetaLR 0.59
- MetaSVM -0.23
- CADD 14.80
- PolyPhen-2 0.04
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available