H21L (p.His21Leu) variant of TNFRSF1B (P20333)
H21L (p.His21Leu) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
H21L (p.His21Leu) variant details
- p.His21Leu
- gnomAD 1-12167153-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.39
- MetaLR 0.55
- MetaSVM -0.49
- CADD 8.56
- PolyPhen-2 0.00
- SIFT 0.74
- Population evidence available
- Structural context available
- Literature evidence available