H21D (p.His21Asp) variant of TNFRSF1B (P20333)
H21D (p.His21Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
H21D (p.His21Asp) variant details
- p.His21Asp
- gnomAD 1-12167152-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.45
- MetaLR 0.64
- MetaSVM -0.33
- CADD 13.00
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available