E35Q (p.Glu35Gln) variant of TNFRSF1B (P20333)
E35Q (p.Glu35Gln) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
E35Q (p.Glu35Gln) variant details
- p.Glu35Gln
- TOPMed rs1639043827
- gnomAD rs1639043827
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.18
- MetaLR 0.58
- MetaSVM -0.29
- CADD 12.30
- PolyPhen-2 0.09
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available