E15K (p.Glu15Lys) variant of TNFRSF1B (P20333)
E15K (p.Glu15Lys) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
E15K (p.Glu15Lys) variant details
- p.Glu15Lys
- gnomAD 1-12167134-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.26
- MetaLR 0.62
- MetaSVM -0.33
- CADD 18.50
- PolyPhen-2 0.01
- SIFT 0.42
- Population evidence available
- Structural context available
- Literature evidence available