E15D (p.Glu15Asp) variant of TNFRSF1B (P20333)
E15D (p.Glu15Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
E15D (p.Glu15Asp) variant details
- p.Glu15Asp
- gnomAD 1-12167136-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.24
- MetaLR 0.63
- MetaSVM -0.29
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.30
- Population evidence available
- Structural context available
- Literature evidence available