E15A (p.Glu15Ala) variant of TNFRSF1B (P20333)
E15A (p.Glu15Ala) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
E15A (p.Glu15Ala) variant details
- p.Glu15Ala
- gnomAD 1-12167135-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.24
- MetaLR 0.59
- MetaSVM -0.35
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.63
- Population evidence available
- Structural context available
- Literature evidence available