A9V (p.Ala9Val) variant of TNFRSF1B (P20333)
A9V (p.Ala9Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
A9V (p.Ala9Val) variant details
- p.Ala9Val
- TOPMed rs1277388576
- gnomAD rs1277388576
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.28
- MetaLR 0.62
- MetaSVM -0.16
- CADD 20.30
- PolyPhen-2 0.23
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available