A9T (p.Ala9Thr) variant of TNFRSF1B (P20333)
A9T (p.Ala9Thr) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
A9T (p.Ala9Thr) variant details
- p.Ala9Thr
- gnomAD 1-12167116-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.487
- REVEL 0.35
- MetaLR 0.81
- MetaSVM 0.13
- CADD 23.80
- PolyPhen-2 0.89
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 3.1e-06)
- Structural context available
- Literature evidence available