A9S (p.Ala9Ser) variant of TNFRSF1B (P20333)
A9S (p.Ala9Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A9S (p.Ala9Ser) variant details
- p.Ala9Ser
- TOPMed rs1638406704
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.34
- MetaLR 0.81
- MetaSVM 0.13
- CADD 24.70
- PolyPhen-2 0.92
- SIFT 0.20
- Most common in the East Asian population (allele frequency 3.8e-05)
- Structural context available