A8V (p.Ala8Val) variant of TNFRSF1B (P20333)
A8V (p.Ala8Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
A8V (p.Ala8Val) variant details
- p.Ala8Val
- gnomAD 1-12167114-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.14
- MetaLR 0.57
- MetaSVM -0.29
- CADD 17.00
- PolyPhen-2 0.04
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available