A8S (p.Ala8Ser) variant of TNFRSF1B (P20333)
A8S (p.Ala8Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
A8S (p.Ala8Ser) variant details
- p.Ala8Ser
- gnomAD 1-12167113-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.34
- MetaLR 0.72
- MetaSVM 0.01
- CADD 22.90
- PolyPhen-2 0.55
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available