A8D (p.Ala8Asp) variant of TNFRSF1B (P20333)
A8D (p.Ala8Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
A8D (p.Ala8Asp) variant details
- p.Ala8Asp
- gnomAD 1-12167114-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.51
- MetaLR 0.78
- MetaSVM -0.02
- CADD 23.20
- PolyPhen-2 0.86
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available