A5S (p.Ala5Ser) variant of TNFRSF1B (P20333)
A5S (p.Ala5Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
A5S (p.Ala5Ser) variant details
- p.Ala5Ser
- gnomAD 1-12167104-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.23
- MetaLR 0.63
- MetaSVM -0.18
- CADD 15.30
- PolyPhen-2 0.23
- SIFT 0.49
- Population evidence available
- Structural context available
- Literature evidence available